Table 1 Peripheral T-cell lymphomas immunostaining pattern

From: Cyclin D1 expression in peripheral T-cell lymphomas

T-cell lymphoma subtype

No. (%)

 

Cyclin D1

Cyclin D2

Cyclin D3

pStat3

Anaplastic large cell lymphoma, ALK+

8/34 (24%)

10/12 (83%)

12/12 (100%)

13/13 (100%)

Anaplastic large cell lymphoma, ALK−

3/44 (7%)

7/15 (47%)

5/15 (33%)

6/16 (38%)

Peripheral T-cell lymphoma, NOS

3/68 (4%)

   

Angioimmunoblastic T-cell lymphoma

0/24 (0%)

   

Extranodal NK/T-cell lymphoma, nasal type

0/7 (0%)

   

Enteropathy associated T-cell lymphoma

0/4 (0%)

   

Hepatosplenic T-cell lymphoma

0/3 (0%)

   

Cutaneous anaplastic large cell lymphoma

0/5 (0%)

   

Mycosis fungoides

0/5 (0%)

   

Subcutaneous panniculitis-like T-cell lymphoma

0/1 (0%)

   

CD4-positive pleomorphic T-cell lymphoma

0/1 (0%)

   

T-cell large granular lymphocytic leukemia

0/4 (0%)

   

Overall

14/200 (7%)

   
  1. P-value between ALCL, ALK+, and ALCL, ALK-negative for cyclin D1 (P=0.05), cyclin D2 (P=0.28), cyclin D3 (P=0.03), and pSTAT3 (P=0.039).
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