Table 1 Clinicopathologic features of 43 dedifferentiated carcinoma of the endometrium or the ovary

From: Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas

Case number	Tumour site	Age	FIGO stage	BRG1		INI1		ARID1A		ARID1B		MMR	Follow-up duration (year)	Follow-up status
				EC	UC	EC	UC	EC	UC	EC	UC
1	Uterus	54	II	+	−	+	+	+	+	+	+	Deficient	0.75	NED
2	Uterus	75	IB	+	−	+	+	−	−	+	+	Deficient	2.75	NED
3	Uterus	54	IA	+	−	+	+	−	−	+	+	Deficient	2.62	NED
4	Uterus	51	IIIC2	+	−	+	+	−	−	+	+	Deficient	1.51	DOD
5	Uterus	66	IA	+	−	+	+	+	+	+	+	Deficient	2.50	NED
6	Uterus	69	II	+	−	+	+	+	+	+	+	Intact	0.61	DOD
7	Uterus	70	IIIC1	+	−	+	+	−	−	+	+	Deficient	1.17	DOD
8	Uterus	73	IA	+	−	+	+	+	+	+	+	Deficient	1.17	DOD
9	Uterus	66	IB	+	−	+	+	−	−	+	+	Deficient	4.00	NED
10	Uterus	65	IV	+	−	+	+	+	+	+	+	Intact	0.13	DOD
11	Uterus	55	IV	+	−	+	+	−	−	+	+	Intact	0.17	DOD
12	Uterus	82	IB	+	−	+	+	−	−	+	+	Deficient	0.83	DOD
13	Uterus	65	IB	+	−	+	+	+	−	+	+	Deficient	3.92	NED
14	Uterus	59	IIIA	+	−	+	+	+	+	+	+	Intact	0.50	DOD
15	Ovary	56	IV	+	−	+	+	−	−	+	+	Intact	0.33	DOD
16	Uterus	54	IIIC1	+	−	+	+	+	+	+	+	Intact	1.12	DOD
17	Uterus	54	IA	+	+	+	−	+	+	+	+	Intact	1.25	NED
18	Uterus	46	IA	+	+	+	−	+	+	+	+	Intact	4.13	NED
19	Uterus	81	IB	+	+	−	−	−	−	+	+	Deficient	3.67	NED
20	Uterus	56	IA	+	+	+	+	+	−	+	−	Deficient	0.25	DOD
21	Uterus	57	II	+	+	+	+	+	−	+	−	Deficient	0.33	NED
22	Uterus	57	IA	+	+	+	+	−	−	+	−	Deficient	1.34	NED
23	Uterus	72	IA	+	+	+	+	−	−	+	−	Deficient	1.42	NED
24	Uterus	63	IIIC1	+	+	+	+	−	−	+	−	Intact	0.45	DOD
25	Uterus	55	IIIB	+	+	+	+	−	−	+	−	Deficient	0.17	DOD
26	Uterus	43	IB	+	+	+	+	−	−	+	−	Deficient	2.40	NED
27	Uterus	81	IB	+	+	+	+	−	−	+	−	Deficient	0.25	DOD
28	Uterus	71	IA	+	+	+	+	−	−	+	−	Deficient	0.92	DOD
29	Uterus	52	III	+	+	+	+	−	−	+	−	Intact	0.08	DOD
30	Ovary	56	II	+	+	+	+	−	−	+	−	Deficient	0.17	DOD
31	Ovary	46	II	+	+	+	+	−	−	+	−	Intact	0.67	DOD
32	Uterus	60	II	+	+	+	+	−	−	+	+	Deficient	6.37	NED
33	Uterus	56	IA	+	+	+	+	−	−	+	+	Intact	0.42	NED
34	Uterus	68	IB	+	+	+	+	−	−	+	+	Deficient	0.50	NED
35	Uterus	93	IB	+	+	+	+	+	+	+	+	Deficient	0.40	DOD
36	Uterus	73	IIIA	+	+	+	+	+	+	+	+	Deficient	0.86	DOD
37	Uterus	60	IB	+	+	+	+	+	+	+	+	Deficient	1.83	NED
38	Uterus	69	IB	+	+	+	+	−	−	+	+	Deficient	NA	NA
39	Uterus	39	IA	+	+	+	+	+	+	+	+	Intact	2.00	NED
40	Uterus	56	IIIA	+	+	+	+	+	+	+	+	Intact	3.41	DOD
41	Uterus	73	IB	+	+	+	+	+	+	+	+	Deficient	3.75	NED
42	Uterus	65	III	+	+	+	+	−	−	+	+	Deficient	4.75	NED
43	Uterus	49	III	+	+	+	+	+	+	+	+	Intact	NA	NA

Abbreviations: DOD, died of disease; EC, endometrioid component; MMR, mismatch repair protein status by immunohistochemistry; NA, information not available; NED, no evidence of disease; UC, undifferentiated component.

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Table 1 Clinicopathologic features of 43 dedifferentiated carcinoma of the endometrium or the ovary

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