Table 2 Logistic regression analysis of number of histopathological risk factors predicting lymph node metastasis

From: Colorectal carcinomas with submucosal invasion (pT1): analysis of histopathological and molecular factors predicting lymph node metastasis

Number of adverse histopathological risk factors a

No. of cases

No. node-positive (%)

Odds ratio (95% CI)

P-value

None

28

1 (3.5)

Referent

0.02

1

88

27 (30.6)

12.0 (1.5–92.5)

 

None

28

1 (3.5)

Referent

 

1

53

11 (20.8)

7 (0.9–58)

0.06

2

21

7 (33.3)

14 (1.5–121)

0.02

3

14

9 (64)

49 (5.0–473)

0.001

  1. aAdverse histopathological risk factors include high tumor budding, >1000 μm submucosal invasion, lymphatic invasion, and high tumor grade.