Table 3 Multivariable logistic regression analysis of histopathological factors predicting lymph node metastasis

From: Colorectal carcinomas with submucosal invasion (pT1): analysis of histopathological and molecular factors predicting lymph node metastasis

Histopathological feature

Multivariable odds ratio (95% CI)

P-value

Grade

 Low

Referent

0.5

 High

1.7 (0.4–8.6)

 

Depth of invasion

 <1000 μm submucosal invasion

Referent

0.2

 >1000 μm submucosal invasion

2.2 (0.7–6.8)

 

Lymphatic invasion

 Absent

Referent

0.1

 Present

2.6 (0.8–8.1)

 

Tumor budding

 Low (0-4 per 0.95 mm2)

Referent

0.004

 High (5 per 0.95 mm2)

4.3 (1.6–11.5)