Table 3 Multivariable logistic regression analysis of histopathological factors predicting lymph node metastasis
Histopathological feature | Multivariable odds ratio (95% CI) | P-value |
---|---|---|
Grade | ||
Low | Referent | 0.5 |
High | 1.7 (0.4–8.6) | |
Depth of invasion | ||
<1000 μm submucosal invasion | Referent | 0.2 |
>1000 μm submucosal invasion | 2.2 (0.7–6.8) | |
Lymphatic invasion | ||
Absent | Referent | 0.1 |
Present | 2.6 (0.8–8.1) | |
Tumor budding | ||
Low (0-4 per 0.95 mm2) | Referent | 0.004 |
High (⩾5 per 0.95 mm2) | 4.3 (1.6–11.5) |