Table 2 Clinicopathologic features of study population

From: Fatty acid-binding protein 1 is preferentially lost in microsatellite instable colorectal carcinomas and is immune modulated via the interferon γ pathway

Clinicopathologic features

All tumors (695)

MSI (n=133)

MSS (n=562)

P-value

Age at surgery

 Mean

72

77

71

<0.0001

 Range

33–99

41–97

33–99

 

Sex

 Male

330 (47%)

37 (28%)

293 (52%)

<0.0001

 Female

365 (53%)

96 (72%)

269 (48%)

 

Location a

 Right

263 (38%)

91 (69%)

172 (31%)

<0.0001

 Transverse

66 (10%)

30 (23%)

36 (6%)

 

 Left

364 (52%)

11 (8%)

353 (63%)

 

Grade b

 Low

549 (79%)

78 (59%)

471 (84%)

<0.0001

 High

143 (21%)

54 (41%)

89 (16%)

 

Stage

 I

112 (16%)

16 (12%)

96 (17%)

<0.0001

 II

245 (35%)

77 (58%)

168 (30%)

 

 III

312 (45%)

39 (29%)

273 (49%)

 

 IV

26 (4%)

1 (1%)

25 (4%)

 

Tumor size

4.4 cm

5.1

4.2

<0.0001

Lymphovascular invasion

 Present

325 (47%)

49 (37%)

276 (49%)

0.01

 Absent

370 (53%)

84 (63%)

286 (51%)

 

Lymph node metastasis

 Present

313 (45%)

39 (29%)

274 (49%)

<0.0001

 Absent

382 (55%)

94 (71%)

288 (51%)

 
  1. Abbreviations: MSI, microsatellite instable; MSS, microsatellite stable.
  2. aSite missing for two cases (one MSI case and one MSS case).
  3. bGrade missing for three cases (one MSI case and two MSS cases).