Figure 4

RT-PCR evaluation of differentially expressed microRNAs. (a) Mean log2 (fold change) from normal brain for the tumor types with n>3 in our data set (subependymal giant cell astrocytoma, pilocytoic astrocytoma, pleomorphic xanthoastrocytoma, ganglioglioma, and dysembryoplastic neuroepithelial tumor) for miRNAs further evaluated in RT-PCR experiments. (b) RT-PCR results for microRNAs that were upregulated in low-grade glial and glioneuronal tumors. (c) RT-PCR results for microRNAs that were downregulated in low-grade glial and glioneuronal tumors. *P<0.05, **P<0.01.