Table 3 Correlations between initial variables and principal components

From: Identification of microRNA expression profile related to lymph node status in women with early-stage grade 1–2 endometrial cancer

Principal component 1

Principal component 2

microRNA

correlation

P-value

microRNA

correlation

P-value

miR-34b-5p

0.85

5.03e−11

miR-129-5p

0.71

1.30e−06

miR-34c-5p

0.85

8.83e−11

miR-34c-3p

0.65

1.56e−05

miR-34c-3p

0.64

2.93e−05

miR-6068

0.63

3.43e−05

miR-184

0.53

8.87e−04

miR-5001-5p

0.63

3.51e−05

miR-504-5p

0.50

1.80e−03

miR-4467

0.48

2.80e−03

miR-148a-3p

0.40

1.61e−02

miR-34c-5p

0.44

6.74e−03

miR-129-5p

−0.45

5.33e−03

miR-34b-5p

0.43

8.98e−03

miR-6068

−0.51

1.57e−03

miR-148a-3p

-0.45

6.06e−03

miR-5001-5p

−0.60

1.43e−04

   
  1. The first principal component, accounting for 32.02% of the variance, was dominated by tumor-suppressor microRNAs, especially of the miR-34 family, including miR-34b-5p, miR-34c-5p, and miR-34c-3p. The second component, accounting for 24.31% of the variance, was dominated by miR-129-5p.