Table 4 Optimal fold-change cutoffs denoting the strongest correlation between microRNA expression and LN status in histologic grade 1–2 EC primary tumor specimens
EC FFPE primary tumor Negative LN N=27 | EC FFPE primary tumor Positive LN N=9 | P-value | |
|---|---|---|---|
miR-375 | |||
FC>0.30 | 20 (95.2%) | 1 (4.8%) | 0.001 |
FC<0.30 | 7 (46.7%) | 8 (53.3%) | |
miR-184 | |||
FC>0.30 | 23 (88.5%) | 3 (11.5%) | 0.006 |
FC<0.30 | 4 (40.0%) | 6 (60.0%) | |
miR-34c-5p | |||
FC>0.0852 | 18 (90.0%) | 2 (10.0%) | 0.049 |
FC<0.0852 | 9 (56.3%) | 7 (43.7%) | |
miR-34b-5p | |||
FC>0.09 | 23 (85.2%) | 4 (14.8%) | 0.026 |
FC<0.09 | 4 (44.4%) | 5 (55.6%) | |
miR-148a-3p | |||
FC>0.50 | 22 (88.0%) | 3 (12.0%) | 0.012 |
FC<0.50 | 5 (45.5%) | 6 (54.5%) | |
miR-129-5p | |||
FC>1.45 | 3 (37.5%) | 5 (62.5%) | 0.013 |
FC<1.45 | 24 (85.7%) | 4 (14.3%) | |
miR-4467 | |||
FC>1.75 | 3 (42.9%) | 4 (57.1%) | 0.0497 |
FC<1.75 | 24 (82.8%) | 5 (17.2%) |
