Figure 4
From: microRNA in situ hybridization for miR-211 detection as an ancillary test in melanoma diagnosis
Chromogenic miRNA in situ hybridization using branched DNA probe also confirmed diffuse miR-211 expression in the nevus nests (red cytoplasmic grains) (a and b). Similarly, the nevic component (c and d) in an invasive melanoma strongly expressed miR-211. In contrast, miR-211 expression was entirely lost in the melanoma area (e and f) of the same lesion. Original magnifications: (a, c) and (e), × 100; and (b), (d) and (f), × 600.
