Table 4 Clinicopathological correlation between fluorescent miR-211 intensity and melanoma American Joint Committee on Cancer parameters
From: microRNA in situ hybridization for miR-211 detection as an ancillary test in melanoma diagnosis
Parameter | n | miR-211 intensity, mean±s.d. | Median | Interquartile range | P-valuea |
|---|---|---|---|---|---|
Gender | |||||
Female | 12 | 35.5±15.8 | 31.6 | 10.2 | 0.04 (non-parametric)/0.33 (t-test) |
Male | 9 | 26.5±25.5 | 20.1 | 17.6 | |
Age, years | |||||
<60 | 8 | 23.8±9.1 | 26.9 | 14.8 | 0.21 |
≥60 | 13 | 36.5±24.1 | 30.8 | 21.8 | |
Pathological stage | |||||
I | 4 | 32.7±11.2 | 31.4 | 14.5 | 0.52 |
II, IIA, IIB, III | 15 | 32.7±23.2 | 29.5 | 20.6 | |
Ulceration | |||||
Absent | 5 | 32.6±9.7 | 32.3 | 1.8 | 0.40 |
Present | 5 | 37.4±30.6 | 30.1 | 10.7 | |
Breslow’s thickness | |||||
<1.0 | 4 | 32.7±11.2 | 31.4 | 14.5 | 0.75 |
≥1.0 | 6 | 36.5±27.5 | 30.4 | 12.2 | |
Clark’s level | |||||
III | 6 | 39.4±27.6 | 31.4 | 27.2 | 0.75 |
IV/IV | 4 | 28.3±5.5 | 30.4 | 6.4 | |
Mitotic index (/mm2) | |||||
0, 1 | 3 | 36.8±9.3 | 32.3 | 17.0 | 0.36 |
≥3 | 7 | 34.2±25.8 | 30.1 | 12.2 | |
Solar elastosis | |||||
Absent | 4 | 28.3±5.4 | 30.3 | 6.2 | 0.59 |
Present | 6 | 39.4±35.0 | 27.6 | 31.6 | |
