Table 4 Correlation of melanoma-FISH and myPath gene expression score with the expert histopathologic interpretation and interest correlation for subcategories of challenging cases

From: Comparison between melanoma gene expression score and fluorescence in situ hybridization for the classification of melanocytic lesions

 

Sensitivity (%)

Specificity (%)

Agreement (%)

No. of cases

(A) Challenging spitzoid lesions

 FISH vs Histology

50

79

67

37

 myPath vs Histology

30

89

58

 

 FISH vs myPath

  

78

 

(B) Challenging nevoid lesions

 FISH vs Histology

62

83

71

35

 myPath vs Histology

64

75

68

 

 FISH vs myPath

  

62

 

(C) All challenging cases a

 FISH vs Histology

56

83

70

78*

 myPath vs Histology

52

80

64

 

 FISH vs myPath

  

70

 
  1. A—challenging spitzoid cases; B—challenging nevoid cases; C—all challenging cases.
  2. aThree ‘traumatized nevus vs regressed melanoma’ lesions and three blue nevus-like lesions.
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