Table 1 Clinical characteristics of study patients

From: Clinicopathologic and genetic characteristics of young patients with pleural diffuse malignant mesothelioma

Characteristic

Patients≤35, N=36 (%)

Patients>35, N=48 (%)

P-value

Sex

 M

19 (53)

42 (87)

0.0005

 F

17 (47)

6 (13)

 

Age

 Mean

30

69

<0.0001

 Range

18–35

38–84

 

History of mantle radiation

  

 Present

8 (22)

0 (0)

0.0007

 Absent

28 (78)

48 (100)

 

Asbestos exposure

 

 Present

11 (31)

36 (75)

0.0001

 Absent

25 (69)

12 (25)

 

Personal history of malignancy

 Present

13 (36)

13 (27)

0.48

 Absent

23 (64)

35 (73)

 

Family history of malignancy

 Present

15 (42)

35 (73)

0.003

 Absent

21 (58)

13 (27)

 

Stage a

 I

3 (12)

1 (7)

0.39

 II

2 (8)

0 (0)

 

 III

16 (64)

10 (72)

 

 IV

4 (16)

3 (21)

 
  1. aStage was available for 25 young patients and 14 older patients. Patients with stage I–II and stage III–IV disease were combined for purposes of statistical analysis using the Fisher exact test.
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