Table 2 Histologic characteristics of mesothelioma in study patients
Characteristic | All histologic types | Epithelioid mesotheliomas | ||||
|---|---|---|---|---|---|---|
Patients≤35 n=36 (%) | Patients>35 n=48 (%) | P-value | Patients≤35 n=28 (%) | Patients>35 n=27 (%) | P-value | |
Histologic type | ||||||
Epithelioid | 28 (78) | 27 (56) | 0.12 | — | — | — |
Mixed | 7 (19) | 19 (40) | — | — | —- | |
Sarcomatoid | 1 (3) | 2 (4) | — | — | — | |
Lymphovascular invasion | ||||||
Present | 12 (33) | 8 (17) | 0.12 | 9 (32) | 3 (11) | 0.10 |
Absent | 24 (67) | 40 (83) | 19 (68) | 24 (89) | ||
Lymph node metastases | ||||||
Present | 15 (42) | 11 (23) | 0.95 | 14 (50) | 6 (22) | 0.05 |
Absent | 21 (58) | 37 (77) | 14 (50) | 21 (78) | ||
Predominant growth pattern | ||||||
Tubulopapillary | 15 (42) | 11 (23) | 0.26 | 15 (54) | 7 (26) | 0.15 |
Papillary | 1 (3) | 1 (2) | 2 (7) | 1 (4) | ||
Solid | 19 (52) | 32 (67) | 10 (36) | 17 (63) | ||
Micropapillary | 1 (3) | 1 (2) | 1 (3) | 1 (4) | ||
Othera | 0 (0) | 3 (6) | 0 (0) | 1 (4) | ||
Nuclear grade | ||||||
Low | 8 (22) | 7 (15) | 0. 09 | 7 (25) | 3 (11) | 0.34 |
Intermediate | 19 (53) | 36 (75) | 17 (61) | 21 (78) | ||
High | 9 (25) | 5 (10) | 4 (14) | 3 (11) | ||
Mitotic Index | ||||||
>4 | 13 (36) | 14 (29) | 0. 64 | 6 (21) | 7 (26) | 0.76 |
≤4 | 23 (64) | 34 (71) | 22 (79) | 20 (74) | ||
