Table 3 Comparison of pathologic features between SOX2-negative and -positive groups
SOX2 negative | SOX2 positive | P-value | |
|---|---|---|---|
(n=8) | (n=105) | ||
Tumor size | |||
Median | 65 mm | 33 mm | 0.270 |
Range | 18–117 mm | 5–140 mm | |
Location | |||
Cervical | 1 (13%) | 4 (4%) | 0.016 |
Thoracic | 5 (62%) | 98 (93%) | |
Abdominal | 0 | 3 (3%) | |
Diffuse | 2 (25%) | 0 | |
Degree of differentiation | |||
Well to moderately | 3 (38%) | 101 (89%) | 0.002 |
Poorly | 5 (62%) | 12 (11%) | |
Vascular invasion | |||
Present | 6 (75%) | 31 (30%) | 0.014 |
Absent | 2 (25%) | 74 (70%) | |
Lymphatic invasion | |||
Present | 8 (100%) | 50 (48%) | <0.001 |
Absent | 0 | 55 (52%) | |
pT classification | |||
pT1 | 2 (25%) | 82 (78%) | 0.003 |
pT2–4 | 6 (75%) | 23 (22%) | |
Lymph node metastasis | |||
Present | 6 (75%) | 70 (67%) | 0.026 |
Absent | 2 (25%) | 35 (33%) | |
pStage | |||
pStage I | 2 (25%) | 64 (61%) | 0.007 |
pStages II–IV | 6 (75%) | 41 (39%) | |
Recurrence | |||
Present | 5 (62%) | 18 (17%) | 0.009 |
Absent | 3 (38%) | 87 (83%) | |
Disease-specific mortality | 4 (50%) | 8 (8%) | 0.004 |
