Figure 1 | Modern Pathology

Figure 1

From: Inflammatory leiomyosarcoma is a distinct tumor characterized by near-haploidization, few somatic mutations, and a primitive myogenic gene expression signature

Figure 1

Representative images of inflammatory leiomyosarcoma case 5 (a, c, e) and case 7 (b, d, f). Hematoxylin–eosin stain (a, b), α-smooth muscle actin immunohistochemistry (c, d), and desmin immunohistochemistry (e, f). Case 5 shows tumor cells with partly epithelioid, partly spindled morphology, intermingled with lymphocytes. The tumor cells in case 7 show a rather plump ovoid morphology with some lymphocytes and macrophages in the background. Both tumors show a strong and diffuse expression of desmin. Note the variable expression of α-smooth muscle actin in inflammatory leiomyosarcoma.

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