Figure 1

Pathologic features of aggressive non-alcoholic steatohepatitis in patient 2. (a) and (b) Examples of severe centrizonal scarring with pericellular fibrosis. Asterisks indicate portal tracts. (c) Prominent ballooned hepatocytes with Mallory–Denk bodies. (d) Centrizonal arteries (arrowheads) in fibrous central zones. (e) Ductular reaction and cholestasis. (f) Perivenular sclerosis with central vein occlusion. (a-f: H&E stain; original magnification: (a): × 40; (b): × 100; (c-f): × 200). H&E, hematoxylin and eosin.