Figure 4
From: Intramucosal lipomas of the colon implicate Cowden syndrome

S-100 immunostaining. (a) Intramucosal lipoma (× 400), S-100 delicately highlights the adipocyte outer membrane (arrows) and occasionally a nucleus within plane of section. (b) Pseudolipomatosis coli (× 400), S-100 does not highlight the insufflation artifact (arrow), but rather stains only lamina propria dendritic cells (arrowheads) for which care should be taken not to over interpret as a false-positive S-100 staining in pseudolipomatosis.