Figure 4

KRAS and IDH1 mutations. (a) The frequencies and resultant amino acid substitutions of gene mutations are summarized. *P<0.05 vs perihilar cholangiocarcinomas; ^†P<0.05 vs hilar cholangiocarcinomas. (b,c) A representative case with a KRAS (G12D) or IDH1 (R132C) mutation.