Figure 1

Genomic alterations in 14 follicular dendritic cell sarcoma samples. (a) Whole genome view. Vertical bars/alternating coloration delineate boundaries for chromosomes 1–22, X and Y. Top panel: aggregate (stacked calls) of all copy-number calls in this data set (red=single copy loss, dark red=two or greater copy loss, blue=single copy gain, dark blue=two or greater copy gain); y-axis: percentage of cases (n=14) with copy-number calls (only). SROs: brackets indicate smallest regions of overlap for genomic regions recurrently altered by losses/loss-of-heterozygosity in ≥45% abnormal cases (see also Table 2). Bottom panel: Copy-number and loss-of-heterozygosity (yellow) calls within individual cases. ≥2 copy-number alterations are displayed as stacked bars. (b) Chromosome Summary view with aggregate of copy-number/loss-of-heterozygosity calls by chromosome. Left side: losses/loss-of-heterozygosity, right side: gains. Asterisks: recurrently altered regions.