Table 2 Overall survival by a multivariable Cox model of the 75 small bowel carcinomas patients with complete stage data

From: Small bowel carcinomas in celiac or Crohn’s disease: distinctive histophenotypic, molecular and histogenetic patterns

 

Hazard ratio (95% CI)

P-value

Clinical group

 

0.033

 Celiac disease-associated carcinomas

1.00 (base)

 

 Crohn’s disease-associated carcinomas

4.98 (1.35–18.34)

0.016a

 Sporadic carcinomas

2.48 (0.66–9.29)

0.176a,b

Stages III–IV vs stages I–II

9.31 (3.30–26.26)

<0.001

CD3+ tumor-infiltrating lymphocytes >15/high-power field vs ≤15

0.15 (0.03–0.69)

0.015

Glandular histotype vs non-glandularc

0.37 (0.16–0.84)

0.018

  1. Model: LR chi2(5)=56.72, P-value<0.001; Harrell’s C=0.87; shrinkage coefficient=0.91.
  2. aFor post hoc comparisons among the clinical groups, significance after Bonferroni’s correction set at 0.017.
  3. bHazard ratio (95% CI): 0.50 (0.22–1.14), P-value=0.098 vs Crohn’s disease-associated small bowel carcinomas.
  4. cMedullary histotype included among non-glandular cases.
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