Table 4 Relationship between pathologic complete response rate, Magee Equation 3 score categories, and pre-therapy nuclear grade

From: Magee Equation 3 predicts pathologic response to neoadjuvant systemic chemotherapy in estrogen receptor positive, HER2 negative/equivocal breast tumors

Categorization by

Subdivision by

N

Pathologic complete responseN (%)

P valuea

Magee Equation 3 scores

Nuclear grade

   

 High (score ≥31)

 1 or 2

3

1 (33%)

 
 

 3

50

19 (40%)

1.0000

 Intermediate (score 18-<31)

 1 or 2

68

1 (1%)

 
 

 3

44

3 (7%)

0.2980

 Low (score <18)

 1 or 2

41

0 (0%)

 
 

 3

15

0 (0%)

NA

Nuclear grade

Magee Equation 3 scores

   

 1

 High (score ≥31)

0

NA

 
 

 Intermediate or low (score <31)

7

0 (0%)

NA

 2

 High (score ≥31)

3

1 (33%)

 
 

 Intermediate or low (score <31)

102

1 (1%)

0.0566

 3

 High (score ≥31)

50

19 (38%)

 
 

 Intermediate or low (score <31)

59

3 (5%)

<0.0001

  1. NA, not applicable.
  2. Pre-therapy nuclear grade available on 221 cases.
  3. aP-value is obtained from two-sided Fisher exact test.