Figure 6 | Modern Pathology

Figure 6

From: Natural killer-like signature observed post therapy in locally advanced rectal cancer is a determinant of pathological response and improved survival

Figure 6

Investigating the influence of CD56 immunohistochemistry positivity on overall survival in post-therapeutic locally advanced rectal cancer validation tissue microarray (n=149)*. (a) Kaplan–Meier curves showing overall survival of all patients (tumor regression grade 1–3) based on CD56 positivity (HR=0.282, 95% CI=0.109–0.729, χ2=7.854, log-rank P=0.005). (b) Kaplan–Meier curves showing overall survival of CD56-positive patients within tumor regression grade 3 subgroup (HR=0.404, 95% CI=0.081–2.004, χ2=1.317, log-rank P=0.251). (c) Kaplan–Meier curves showing overall survival of CD56-positive patients within tumor regression grade 2 subgroup (HR=0.323, 95% CI=0.094–1.109, χ2=3.621, log-rank P=0.057) (d) Kaplan–Meier curves showing overall survival of CD56-positive patients within tumor regression grade 1 subgroup (HR=0.036, 95% CI=0.000–116.410, χ2=1.677, log-rank P=0.195). *One patient from CD56 immunohistochemistry validation tissue microarray did not have survival data.

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