Figure 3
From: EWSR1 fusion proteins mediate PAX7 expression in Ewing sarcoma
Strong and diffuse PAX7 expression in Ewing sarcoma, including EWSR1-FLI1 and EWSR1-ERG variants. (a) Representative immunohistochemical detection of PAX7 expression in Ewing sarcoma. (b) Representative immunohistochemical analysis of ERG and PAX7 expression in Ewing sarcoma. Shown are examples of Ewing sarcoma with the EWSR1-ERG fusion (top), which shows diffuse anti-ERG immunoreactivity, and the EWSR1-FLI1 fusion (bottom), which shows no anti-ERG immunoreactivity.
