Figure 1 | Modern Pathology

Figure 1

From: Genetic evaluation of juvenile xanthogranuloma: genomic abnormalities are uncommon in solitary lesions, advanced cases may show more complexity

Figure 1

Histopathology of selected juvenile xanthogranuloma lesions with abnormal genomic profiles. (a–c). Hematoxylin and eosin stain (× 200). Juvenile xanthogranuloma lesions display diffuse fibrohistiocytic proliferations with bland round to oval nuclei, admixed lymphocytes and occasional eosinophils. Touton giant cells (shown in b and c) are also common. (a–b). Two distinct lesions (JXG-1a and JXG-1b, respectively) from a single patient with disseminated juvenile xanthogranuloma. (c). A solitary cutaneous lesion (JXG-3).

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