Table 3 Rearrangements identified in our series
Case # | Gene 1 | Gene 2 | Site 1 description | Site 2 description | Fusion |
|---|---|---|---|---|---|
FGFR2 fusions | |||||
#11 | FGFR2 | CEP55 | Exon 17 of FGFR2 | Exon 2 of CEP55 | Protein fusion: in frame (FGFR2-CEP55) |
#12 | FGFR2 | SASS6 | Intron of FGFR2(−): 80 bp after exon 16 | Intron of SASS6(−): 586 bp before exon 7 | Protein fusion: in frame (FGFR2-SASS6) |
#14 | FGFR2 | DISP1 | Intron of FGFR2(−): 276 bp before exon 17 | Intron of DISP1(+): 9Kb after exon 2 | Protein fusion: out of frame (DISP1-FGFR2) |
#14 | FGFR2 | TXLNA | Intron of FGFR2(−): 687 bp before exon 17 | Intron of TXLNA(+): 1kb before exon 5 | Protein fusion: in frame (FGFR2-TXLNA) |
#15 | VCL | FGFR2 | Exon 13 of VCL(+) | Intron of FGFR2(−): 535 bp before exon 17 | Protein fusion: mid-exon (FGFR2-VCL) |
ALK fusion a | |||||
#18 | STRN | ALK | Exon 3 of STRN (NM-003162) | Exon 20 of ALK (NM-004304) | Protein fusion: in frame (STRN-ALK) |
