Figure 6 | Modern Pathology

Figure 6

From: Altered peritumoral microRNA expression predicts head and neck cancer patients with a high risk of recurrence

Figure 6

Workflow to predict novel drug compounds for locally advanced recurrent head and neck squamous cell carcinoma. Scheme representing the workflow and the results relative to the identification by LINCS database of the genetic manipulations perturbing mRNAs positively (mRNAs-PCm) and negatively (mRNAs-NCm) correlated to the miRNAs deregulated in peritumoral tissue. *Genes deregulated in peritumoral vs normal tissues and in tumoral vs normal tissues. Mean rank score (best 4 cell lines) >90 for positive score and <−90 for negative score. Si, silencing.

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