Table 1 Clinicopathologic characteristics of invasive lobular carcinoma cases
All cases | Phenotype | ||||
|---|---|---|---|---|---|
ER + /HER-2 − | ER + /HER-2 + | ER − /HER-2 + | ER − /HER-2 − | ||
Total number (n) | 47 | 33 | 8 | 1 | 5 |
Age (years) | |||||
Mean (range) | 59 (34–87) | 58 (34–79) | 62 (41–78) | 87 | 62 (43–84) |
Race | |||||
White | 37 (79%) | 24 (73%) | 8 (100%) | 1 (100%) | 4 (80%) |
Black | 5 (11%) | 5 (15%) | 0 (0%) | 0 (0%) | 0 (0%) |
Asian | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
Hispanic | 3 (6%) | 2 (6%) | 0 (0%) | 0 (0%) | 1 (20%) |
Other | 2 (4%) | 2 (6%) | 0 (0%) | 0 (0%) | 0 (0%) |
Grade | |||||
I | 5 (11%) | 4 (12%) | 1 (13%) | 0 (0%) | 0 (0%) |
II | 34 (72%) | 27 (82%) | 6 (74%) | 0 (0%) | 1 (20%) |
III | 8 (17%) | 2 (6%) | 1 (13%) | 1 (100%) | 4 (80%) |
Mean tumor size (cm) | 2.8 | 2.7 | 2.7 | 7.1 | 3.2 |
Stage | |||||
I | 16 (34%) | 16 (49%) | 0 (0%) | 0 (0%) | 0 (0%) |
II | 20 (43%) | 10 (30%) | 7 (87%) | 0 (0%) | 3 (60%) |
III | 11 (23%) | 7 (21%) | 1 (13%) | 1 (100%) | 2 (40%) |
IV | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
Subsequent metastatic disease | |||||
Yes | 5 (11%) | 1 (3%) | 1 (13%) | 1(100%) | 2 (40%) |
No | 42 (89%) | 32 (97%) | 7 (87%) | 0 (0%) | 3 (60%) |
Death due to disease | |||||
Yes | 4 (9%) | 1 (3%) | 1 (13%) | 0 (0%) | 2 (40%) |
No | 43 (91%) | 32 (97%) | 7 (87%) | 1 (100%) | 3 (60%) |
