Figure 6
From: Pathologic assessment of gastrointestinal tract and pancreatic carcinoma after neoadjuvant therapy
(a) The esophagectomy specimen demonstrates columnar mucosa involving the distal esophagus with only subtle mucosal irregularities and no distinct mass. (b) Histologic evaluation demonstrated Barrett’s esophagus associated with abundant mural mucin that was predominantly acellular (× 40). (c) Acellular mucin was also seen within the lymph nodes of the esophagectomy; however, this should not be interpreted as metastatic disease (× 40). (d) The entire tumor bed from the esophagectomy was submitted for histologic examination and rare groups of adenocarcinoma cells (<10% of tumor bed) with cytologic features of therapy effect were identified in the mucin pools, corresponding to a CAP tumor regression grade score 1 (× 200).
