Figure 8
From: Pathologic assessment of gastrointestinal tract and pancreatic carcinoma after neoadjuvant therapy
(a) Cytoplasmic vacuolization characterized by tumor cells with relatively small, pyknotic irregular nuclei is commonly seen in pancreatic ductal adenocarcinoma following neoadjuvant therapy (× 200). (b) The residual ductal adenocarcinoma in this patient who received neoadjuvant therapy demonstrates abundant cytoplasmic eosinophilia with bizarre, hyperchromatic nuclei (× 200). (c) The background non-neoplastic pancreas can display extensive acinar atrophy and fibrosis with residual benign ducts associated with enlargement of the islets (white arrow) (× 40).
