Table 2 Schemes for tumor regression grade in hepatic colorectal metastases after neoadjuvant therapy
From: Pathologic assessment of gastrointestinal tract and pancreatic carcinoma after neoadjuvant therapy
Tumor regression grading scheme (references) | Score | Criteria |
---|---|---|
Rubbia-Brandt52 | Major response | Fibrosis without detectable tumor; or fibrosis with rare, scattered residual cancer cells |
Minor response | Fibrosis and tumor cells with a predominance of fibrosis | |
No response | Fibrosis and tumor cells with a predominance of tumor cells, or no changes of regression | |
Blazer55 | Complete response | No residual carcinoma |
Major response | 1–50% residual carcinoma | |
Minor response | >50% residual carcinoma |