Table 4 Univariate log-rank analysis for disease-specific survival on the test set including OHbIC (n=65 patients)

From: An oral cavity squamous cell carcinoma quantitative histomorphometric-based image classifier of nuclear morphology can risk stratify patients for disease-specific survival

Variable

Disease-specific survival HR (95% CI)

P-value

Age

≤60 vs >60

0.39 (0.12–1.26)

0.103

Race

Nonwhite vs white

0.80 (0.20–3.26)

0.7435

Path histology

Well/moderately differentiated vs poorly differentiated

1.93 (0.59–6.29)

0.3006

T-stage

T1/T2 vs T3/T4

2.62 (0.86–8.03)

0.0855

N-stage

N0 vs N1/N2

1.66 (0.89–3.08)

0.1088

N-stage

N0/N1 vs N2

2.14 (0.69–6.61)

0.1771

Comorbidity score

Non/mild vs moderate/severe

3.02 (0.80–11.45)

0.1047

Overall stage

I/II vs III/IV

3.71 (0.82–16.80)

0.0519

Chemotherapy

Yes vs no

1.96 (0.40–9.66)

0.4359

Treatment

Surgery only vs postoperative/definitive

1.75 (0.47–6.48)

0.3830

OHbIC

Positive vs negative

3.31 (1.08–10.14)

0.0335

  1. Abbreviations: CI, confidence interval; HR, hazard ratio; OHbIC, oral cavity squamous cell carcinoma quantitative histomorphometric-based image classifier.
  2. Value in bold is statistically significant, P<0.05.
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