Figure 5 | Modern Pathology

Figure 5

From: Detection of 6 TFEB-amplified renal cell carcinomas and 25 renal cell carcinomas with MITF translocations: systematic morphologic analysis of 85 cases evaluated by clinical TFE3 and TFEB FISH assays

Figure 5

Morphologic spectrum of TFE3 translocation renal cell carcinoma, including (a) clear cell renal cell carcinoma-like morphology, H&E, × 200; (b) extensive nuclear pseudoinclusions, H&E, × 200, inset × 400; (c) scattered collections of foamy histiocytes, H&E, × 400, and two cases with TFEB translocation renal cell carcinoma-like morphology including (d) a partial nephrectomy, H&E, × 200, and (e) a needle biopsy, H&E, × 100, inset: × 200, with (f) immunohistochemical expression of pancytokeratin and PAX8 (inset) by tumor cells.

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