Figure 7 | Modern Pathology

Figure 7

From: Detection of 6 TFEB-amplified renal cell carcinomas and 25 renal cell carcinomas with MITF translocations: systematic morphologic analysis of 85 cases evaluated by clinical TFE3 and TFEB FISH assays

Figure 7

Renal cell carcinomas lacking MITF aberrations by TFE3 and TFEB FISH assays. (a) Clear cell renal cell carcinoma with morphology resembling TFE3 translocation renal cell carcinoma, H&E, × 200; (b) high-grade oncocytic papillary renal cell carcinoma, H&E, × 200; (c) unclassified renal cell carcinoma with biphasic populations including smaller cells surrounding psammoma bodies, H&E, × 200; (d) papillary renal cell carcinoma with second population of clear cells and psammomatous calcifications, H&E, × 200; (e) unclassified renal cell carcinoma with voluminous eosinophilic and clear cytoplasm and entrapped benign renal tubules, H&E, × 200; and (f) unclassified renal cell carcinoma with voluminous eosinophilic and clear cytoplasm, H&E, × 200.

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