Figure 3
From: Long-term body weight outcomes of antidepressant–environment interactions
Interactions of recurrent restraint stress (RRS), short-term antidepressant treatment and fat diet on caloric intake, body weight and bone length. (a) Cumulative absolute intake (kcal × 103) during post-restraint stress (days 12–177). Late in the post-stress recovery period (starting on day 133 or 4.4 months), antidepressant-treated animals had significantly higher caloric intake when compared with non-treated RRS animals (R-C, n=13; R-AD, n=25). Inset (b) shows the average of daily caloric intake (days 133–163) for 14 periods. (c) Body length (cm) at day 150; R-C, n=5; R-AD, n=9. Antidepressant-treated RRS had larger bodies. (d) Femur length (cm) was obtained at end of the experiment, day 177. Antidepressant-treated RRS animals had longer femurs. (e) Tibia length was obtained at day 177. Antidepressant-treated RRS animals had longer tibias. *P<0.05; **P<0.01.
