Figure 2

Plotted are mean serum brain-derived neurotrophic factor (BDNF) levels by specific class of antidepressant (St John's wort, selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) and noradrenergic and specific serotonergic antidepressants (NaSSAs)). The dashed line indicates the mean BDNF level of the antidepressant-free depressed group. Error bars reflect the standard error of the mean. *Denotes statistical significance at P<0.05. **Denotes statistical significance at P<0.01.