Table 1 Top hits of the meta-analysis

From: Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM

Marker name

Allele 1

Allele 2

βa

σβb

P-value

Direction c

Chr.

Position

MAF

RSQ

Gene

Feature

rs2470893

t

c

0.0614

0.011

2.39 × 10−08

++++++++++

15

72806502

0.26–0.35

0.79–1

CYP1A1/CYP1A2

Intergenic

rs2472297

t

c

0.0671

0.012

4.18 × 10−08

++++++−+++

15

72814933

0.17–0.31

0.56–1

CYP1A1/CYP1A2

Intergenic

rs6495122

a

c

−0.0551

0.010

8.22 × 10−08

−−−−+−−−−−

15

72912698

0.36–0.46

0.93–1

CPLX3/ULK3

Intergenic

rs16868941

a

g

0.0648

0.0124

1.55 × 10−07

−+++++++++

8

103121553

0.17–2.3

0.93–1

NCALD

Intron[NM_001040630.1]

rs382140

a

g

0.0729

0.0143

3.34 × 10−07

+++++−−+++

7

107569436

0.11–0.21

0.61–1

LAMB4/NRCAM

Intergenic

rs9526558

a

g

0.0595

0.012

6.79 × 10−07

++++++−+++

13

48880513

0.21–0.26

0.97–1

CAB39L

Intron[NM_001079670.1]

  1. Abbreviations: Chr., chromosome; MAF, minor allele frequency.
  2. aThe effect estimate of the single-nucleotide polymorphism is shown.
  3. bs.e. of the effect estimate is shown.
  4. cDirection of the effect of allele 1 is shown. See Figure 2 for details.
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