Figure 2
From: A genome-wide survey and functional brain imaging study identify CTNNBL1 as a memory-related gene
CTNNBL1 rs16986890 genotype-depended differences in memory-related brain activity (subsequent memory analysis, see main text) in 322 individuals. Displayed are gene dose-dependent (with increasing number of G-alleles) increases in activity in the parahippocampal gyrus (left figure, coronal section, peak activation at [19 −30 −12]; Pwhole-brain FDR−corrected=0.04, Pnominal< 0.001) and in the medial frontal gyrus/anterior cingulate (right figure, sagittal section, peak activation at [−14 55 0]; Pwhole-brain FDR−corrected=0.01, Pnominal<0.001). Activations were overlaid on sections of a T1-weighted magnetic resonance image of SPM5, displayed at an uncorrected threshold of P=0.001 and using color-coded t-values.
