Table 1 Genotype-dependent performance in word-based episodic memory tasksa in the GWAS sample (Switzerland, n=1073) and the replication sample (Serbia, n=524)
From: A genome-wide survey and functional brain imaging study identify CTNNBL1 as a memory-related gene
Genotype (rs16986890) | GWAS total sample (Switzerland, n=1073) | GWAS subsample 1 (Zurich, n=625) | GWAS subsample 2 (Basel, n=448) | Replication sample (Serbia, n=524) | ||||
---|---|---|---|---|---|---|---|---|
n | Mean±s.e.m. | n | Mean±s.e.m. | n | Mean±s.e.m. | n | Mean±s.e.m. | |
AA | 961 | −0.05±0.03 | 564 | −0.04±0.04 | 397 | −0.07±0.04 | 434 | −0.14±0.06 |
AG | 106 | 0.41±0.11 | 59 | 0.39±0.14 | 47 | 0.43±0.17 | 88 | 0.37±0.16 |
GG | 6 | 1.06±0.37 | 2 | 0.75±0.00 | 4 | 1.21±0.57 | 2 | 0.84±0.70 |
P=0.00000007 ES: d=0.33; r2=0.027 | P=0.0005 ES: d=0.28; r2=0.019 | P=0.00003 ES: d=0.39; r2=0.038 | P=0.003 ES: d=0.26; r2=0.017 |