Figure 3
Association of single-nucleotide polymorphism (SNP) in the FRMD4A locus with plasma Aβ1−42/Aβ1−40 level following meta-analyses of z-score β coefficients under an additive model adjusted for age and gender using three independent healthy populations. SNPs in red are nominally associated with Aβ peptide levels. SNPs in are the three markers defining the AAC haplotype assocated with Alzheimer's disease (AD) risk.
