Table 1 Aβ and Dkk1 induce a common signalling pathway

From: Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway

 

Aβ treated

Dkk1 treated

1

EGR1

EGR1

2

IER2

NAB2

3

NAB2

VCL

4

CCND1

KLF10

5

FOS

TIMP1

6

BAIAP2

FOS

7

ATF6B

CCND1

8

KLF10

CCL20

9

HNRNPL

TUBB6

10

THOC3

RHOQ

  1. Microarray data from Aβ25-35-treated (20 μM, 3 h) primary mouse cortical neurons and Dkk1-treated (800 ng ml−1, 2 h) primary rat cortical neurons were processed (Supplementary Information) and ranked by fold change. The top 10 genes from each treatment are shown.