Figure 1
From: Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology
BIN1 mRNA levels in AD and control brains. All values of BIN1 mRNA are shown as arbitrary units (a.u.) following normalisation by GUS (β-glucuronidase) or β-actin mRNA quantification. mRNA quantifications were carried out in triplicate in all individuals. cross: mean of BIN1 expression in cases and controls; middle line: median; upper horizontal line: inclusion of 75% of the individuals; lower horizontal line: inclusion of 25% of the individuals. *Individuals exhibiting extreme values (out of the global distribution).
