Figure 1 | Molecular Psychiatry

Figure 1

From: Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects

Figure 1

Electroencephalography (EEG) effects of lanicemine relative to ketamine in rodent model. Left: Time course of gamma-band EEG following administration of lanicemine and ketamine (doses: 10 mg kg−1) and respective vehicles. Right: Tolerability of lanicemine vs ketamine, measured by hyper-locomotor activity, at comparable levels of target engagement.

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