Figure 6

Effects of ultrasmall superparamagnetic iron oxide (USPIO) on pregnancy outcomes and liver function in the mother and offspring. (a) Foetal and placental weight at day 16 in USPIO-treated mice were not different from control untreated mice. n=4–5 mice/group. (b) Oxidative stress levels (signal transducer and activator of transcription factor 8 levels) in placentas from USPIO-treated mice were not different from control mice. n=4–5 mice/group. (c) Vascular endothelial growth factor levels in placentas from USPIO-treated mice were not different from control mice. n=4–5 mice/group. (d) Hepatic enzymes (alanine transaminase and aspartate transaminase) activity in the serum in mothers during pregnancy (–day 14) and postpartum (21 days) and offspring in USPIO-treated and control mice.