Figure 3
Associations between the number of pack-years and local cortical thickness (n=259). Areas in orange–yellow shades represent statistically significant associations at a false discovery rate (FDR)=0.05. Color bar represents FDR q-values. For a description of what three-dimensional (3D) perspective each specific brain image represents, see Figure 2 legend. (a) Association between pack-years and cortical thickness controlling only for gender and exact age at scanning. A scatterplot of the association between pack-years and mean cortical thickness within significant areas of thinning is also provided (thickness values in mm). (b) Association between pack-years and cortical thickness controlling for all covariates. A scatterplot of the association between pack-years and mean cortical thickness within significant areas of thinning is also provided (thickness values in mm).
