Figure 2

Regional association plots of genomic regions, which demonstrated genome-wide significance (P<5 × 10−8) in the meta-analysis, for chromosomes 6 (a), 14 (b) and 19 (c). The circles represent each genotyped single-nucleotide polymorphism (SNP), with the color indicating pairwise linkage disequilibrium (LD) in relation to the top hit (calculated from 1000 Genomes Nov 2010 EUR); −log10 P-values are also indicated (y axis). The purple diamond represents the top SNP in each region. The solid blue line indicates the recombination rate.