Figure 3

Plot of effect size against mean age of cohort for rs10119 (top SNP APOE/TOMM40 region). Each numbered point represents a cohort (1, RSIII; 2, ERF; 3, SPLIT; 4, GS; 5, KORCULA; 6, NCNG; 7, GENOA; 8, ORCADES; 9, RSI; 10, FHS; 11, ASPS; 12, BASEII; 13, BETULA; 14, HCS; 15, RSII; 16, HBCS; 17, LBC1936; 18, HRS; 19, OATS; 20, TASCOG; 21, 3C; 22, PROSPER-Netherlands; 23, ROS; 24, PROSPER-Scotland; 25, PROSPER-Ireland; 26, AGES; 27, LBC1921; 28, CHS; 29, MAP). Two cohorts (ARIC and Sydney MAS) did not have data available for rs10119. Dashed regression line and shaded 95% confidence interval are shown. For full details of abbreviations, see Supplementary Information 2: Cohort Abbreviations.