Figure 2
Primary (Y-BOCS) and secondary (HAM-A, HAM-D, GAF) psychiatric outcome measures. Individual test data are shown for the crossover trial (n=17), and for the comparison between the preoperative situation and after 4 years of follow-up (n=18), and at last follow-up (n=24) (a–l). Black arrows in graphs (c), (f), (i) and (l) indicate patients whose last follow-up measurement was taken before capsulotomy (n=3), cessation of stimulation (n=2) or implantation of additional electrodes in the subthalamic nucleus (n=1). These six patients have a follow-up duration of <4 years, and are thus not included in graphs (b), (e), (h) and (k). The dotted arrows in graphs (c), (f), (i) and (l) indicate a patient who is currently not being stimulated, but received stimulation for 10 years, and is thus also included in graphs (b), (e), (h) and (k). Statistically significant differences, as calculated with Wilcoxon's matched-pairs tests (see Table 3 for details), are indicated: *P<0.017, **P<0.001 and ***P<0.0001. 4YFU, 4-year follow-up; GAF, global assessment of functioning; HAM-A, Hamilton Anxiety Rating Scale; HAM-D, Hamilton Depression Rating Scale; LFU, last follow-up; preop, preoperative; Y-BOCS, Yale-Brown Obsessive-Compulsive Scale.
