Table 1 Demographic and clinical characteristics at baseline, and during crossover and follow-up

Patient	Sex	Age (years)	Y-BOCS preop	HAM-A preop	HAM-D preop	GAF preop	Crossover (months PI)	Y-BOCS OFF	Y-BOCS ON	Y-BOCS % impr ON vs OFF	Y-BOCS 4YFU	Y-BOCS % impr 4YFU vs preop	LFU (months PI)	Y-BOCS LFU	Y-BOCS % impr LFU vs preop	Status May 2014	BOL (months PI)	Y-BOCS BOL	Y-BOCS % impr BOL vs preop
1	M	34	38	44	43	35	1	35	30	14	—	—	15	36	5	CAPS	N/A	N/A	N/A
2	F	51	33	38	23	35	4	29	20	31	18	45	132	28	15	ON	67	16	52
3	F	38	30	26	29	30	—	—	—	—	7	77	171	16	47	ON	99	5	83
4	M	34	38	24	17	25	10	35	22	37	—	—	38	30	21	CAPS	28	21	45
5	F	39	34	20	19	25	9	34	25	26	22	35	120	25	26	OFF	66	16	53
6	M	37	30	24	24	35	8	36	12	67	17	43	136	13	57	ON	62	2	93
7	F	39	35	21	16	40	6	35	10	71	6	83	121	8	77	ON	67	2	94
8	M	40	32	9	19	30	—	—	—	—	6	81	121	16	50	ON	58	5	84
9	M	23	31	20	25	35	9	4	2	50	11	65	104	9	71	ON	3	2	94
10	F	29	37	27	21	35	6	23	2	91	4	89	105	2	95	ON	35	1	97
11	F	56	36	30	26	40	6	18	5	72	6	83	101	15	58	ON	76	1	97
12	M	33	37	46	28	25	15	33	22	33	25	32	89	24	35	ON	80	25	32
13	M	31	32	20	21	35	9	32	17	47	6	81	87	20	38	ON	39	3	91
14	F	51	37	22	24	45	12	35	30	14	—	—	24	30	19	STN	85	19	49
15	F	47	34	16	6	40	8	32	21	34	22	35	74	23	32	ON	42	18	47
16	M	59	36	15	25	40	—	—	—	—	18	50	70	15	58	ON	29	2	94
17	M	34	40	30	24	35	—	—	—	—	—	—	28	36	10	CAPS	9	26	35
18	F	50	35	16	18	45	19	19	36	−89	22	37	59	20	43	ON	27	11	69
19	M	24	38	32	24	35	14	34	26	24	—	—	35	35	8	OFF	20	22	42
20	F	26	31	19	25	35	10	27	13	52	19	39	54	19	39	ON	49	19	39
21	F	54	33	22	17	25	31	27	10	63	11	67	51	11	67	ON	39	10	70
22	M	42	33	15	20	45	—	—	—	—	8	76	47	8	76	ON	42	7	79
23	M	52	35	23	27	45	—	—	—	—	10	71	46	10	71	ON	22	7	80
24	F	50	37	29	14	40	—	—	—	—	—	—	22	15	59	OFF	13	12	68
		MED	MED	MED	MED	MED	MED	MED	MED	MED	MED	MED	MED	MED	MED		MED	MED	MED
		39	35	23	24	35	9	32	20	37	11	66	72	18	45		42	10	70

Abbreviations: BOL, best open-label period of minimally 2 months; CAPS, capsulotomy; F, female; GAF, global assessment of functioning; HAM-A, Hamilton Anxiety Rating Scale; HAM-D, Hamilton Depression Rating Scale; LFU, last follow-up; % impr, percentage improvement; M, male; MED, median; N/A, not available (this patient never experienced a clinically significant improvement with DBS); OFF, stimulation off; ON, stimulation on; PI, postimplantation; preop, preoperative; STN, implantation of additional electrodes in subthalamic nucleus; Y-BOCS, Yale-Brown Obsessive-Compulsive Scale; 4YFU, 4-year follow-up.

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