Table 2 Primary events by criterion and in antipsychotic sub-groups

From: Optimal duration of risperidone or olanzapine adjunctive therapy to mood stabilizer following remission of a manic episode: A CANMAT randomized double-blind trial

 

Treatment group

 

0 weeks N=52

24 weeks N=54

52 weeks N=53

Total:

39

29

29

By study criteriona:

 YMRS score of 15 or greater

10

5

7

 HAM-D 21-item score of 15 or greater

16

13

14

 HAM-D suicide item score of 3 or greater

4

5

2

 CGI-S score of 3 or greater

38

27

29

 Patient required hospitalization

8

1

3

 Patient who made a suicide attempt or committed suicide

0

0

0

Antipsychotic sub-groups

 Olanzapine

N=22

N=21

N=23

Mania

3

4

3

Depression

12

6

3

 Risperidone

N=30

N=33

N=30

Mania

11

2

4

Depression

13

17

19

  1. Abbreviations: CGI-S, Clinical Global Impression Severity; HAM-D, Hamilton Depression Rating Scale; YMRS, Young Mania Rating Scale.
  2. aPatients may have met more than one criterion for a primary event.
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