Figure 1 | Molecular Psychiatry

Figure 1

From: Molecular systems evaluation of oligomerogenic APPE693Q and fibrillogenic APPKM670/671NL/PSEN1Δexon9 mouse models identifies shared features with human Alzheimer’s brain molecular pathology

Figure 1

Schematic overview of mouse AD transcriptome analysis. RNA sequencing was performed on the entorhinal cortex and dentate gyrus for three groups of animals (oligomerogenic APPE693Q, fibrillogenic APPKM670/671NL/PSEN1Δexon9 and wild type) comprising a total of 28 samples (Transgenic n=3 and Wild type n=4 samples per comparison). Region-based differential gene and exon expression analysis was performed between all mouse lines, and results were annotated with diverse functional molecular data.

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